Sunday 17 May 2020

Tests and pathways leading to the early detection of Alzheimer's disease

There are 7 stages in Alzheimer's disease (AD) development, and we cannot realise it until stage 3-4 that there is a posibility of something wrong. In stage two there are only few incidents and usually they are identified as ''senior moments'. In stage two there is a very mild cognitive decline, but it is still not observable by the subjects or family or friends. Stage 3 has a mild cognitive decline, and the person may start  to have difficulties remembering names or finding/using words (especially 'fancy' words, as the vocabulary tends to get much simpler). In this stage you realise that something is wrong, but you brush it off, and try to minimasing, blaming age. Stage 4 is a full blown Alzheimer's disease (AD), and according to doctors, you may have on average 12 years left to live once you reach this stage. Which may or may be not true. Up to stage 4, you may still have a chance to delay it significantly or even recover. Just for your curiosity, in stage 5 you start to be confused, have problem with dressing and remembering informations about yourself and short term memory will not work optimally. In stage 6 you may be unaware of your surroundings, do not know where you are, do not remember much about yourself, start to wander around and have toileting accidents. Stage 7 is the terminal one, when you forget how to eat, speak and most of the other basic functions.

But, there is a way to deal with this from stage 2, and this is by using the knowledge already accumulated and test yourself in many way, keeping an eye on your cognitive abilities. Genetical informations are very important, as i already mentioned the ApoE allele involvement in AD in my previous post. By cheching which version of Apolipoprotein you got (E2, E3 or E4), you may have an idea at what age the degenerative process is most probably to start. Checking a service like 23ANDME can provide this information, but i find the price being quite prohibitive (in the £100-150 range). So my advice is to make an account and wait for them to offer some Christmas or Easter promotion, and you may get it done for half the price. Unless is urgent. Inflammation is another very important symptom, and it is closely linked with AD (and many other problems). Some infections are definetely linked with the AD (yes, tick bites, that's what i am talking about - viruses like Herpes Simplex, Borrelia - responsable for Lyme disease, some oral bacteria like Porphyromonas gingivalis, and a number of fungi and moulds). There is one aminoacid called homocysteine, which is causally associated with AD and linked to brain atrophy. Fasting insulin level or blood sugar level is of utmost importance, and some hormonal imbalance has definitely linked to AD. Mycotoxins (moulds) and heavy metals exposure can also be a cause for Alzheimer's disease. There are some other factors observed and almost never mentioned, for example the AD patient may have a distinct gut microbiome, even if we do not knnow yet if it is the microbiome leading to AD or the AD leading to the specific changes in microbiome. The blood-brain barrier is often abnormal in AD patients. And everybody is blaming obesity for many ilnesses, yes, it is to blame for AD also, as a higher BMI will increase the changes to suffer from it. Prediabetes state is also mentioned in some researches (it is related to the insulin resistance and the high levels of blood glucose). 

All this should be checked in an ideal situation, but what really happen in reality? You reach stage 4, you or your relatives or your friends start to worry about the cognitive decline, you check with a doctor, asked to do a MRI to check the brain, have some blood tests like complete blood count, vitamin B12, Thyroid hormone levels ( TFT, TSH T3 maybe) and metabolic panel, and then you are prescribe some generic meds and your partner or children are asked to help with finances and medication. And this is it. A surefire approach to failure. 

What i will talk about in some following posts is how to detect it early, as early as in stage 1-2, and what you need to do to delay it as much as possible. Stay with me and read my future posts (i still need to read a ton of research to realise all the intricaties involved. But i hope it will help you to stay cognitively healthy for longer. 

 

 

5 comments:

  1. Alzheimer's is tough, and the patient, as well as caregivers, go through strenuous conditions. At a Rehabilitation centre in Chennai, it is a norm to give the best care to all patients taking into consideration their mental abilities. We try and reduce the burden of the caregiver. Thanks for sharing this.

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    1. My husband has been diagnosed with Alzheimer's in 2016 there's a herbal foundation in Cape Town they cured my husband  Alzheimer's disease . Pm me i will give their details. People can search about them on Google or youtube (Multivitamin Care ). My husband faced many difficulties and was in several depression, Trouble understanding visual image, aggression ,so many,. This thing happened to him at a very crucial stage of our life. PM if someone needs info or contact them directly Multivitamincare.org  they cured 100% of Alzheimer with their herbal formula .



















































































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    2. THANX TO DOCTOR OSAZE WHO CURE ME FROM HERPES SIMPLEX AND HAERT DIESEASE WITH HIS HERBAL MEDICATION, MY ENTIRE LIFE WAS BECOMING MISERABLE WHEN I CONTACTED THESE DIESEASES, I WENT TO DIFFERENT HOSPITAL IN NEWYORK AND CONNECTICUT TO NO AND VAIL, UNTIL I CAME ACROSS DOCTOR OSAZEE'S TESTIMONIES ONLINE ON HOW HE HAS BEEN USING HIS HERBS TO CURE PEOPLE OF HERPES DIESEASES, AND I DICIDED TO CONTACT HIM AND GIVE HIS MEDICATION A TRY, WITHIN ONE MONTH AND A WEEK I WAS TOTALLY CURED, IN CASE YOU ARE GOING THROUGH SIMILAR PROBLEM AND YOU WANTS TO CONTACT DR OSAZEE, YOU CAN EMAIL HIM ON: DROSAZEHERBAL@GMAIL.COM OR CALL OR WHATSAP HIM ON: +2347089275769

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  2. My dad was diagnosed with Alzheimer's diseases this neuron disease started 25 years before being revealed it was trigged the moment we started eating sugars including any and almost all carbs that break down to glycerol,and he was placed on the best  medical treatment approved by united states,(FDA) he has been taking Cholinesterase,Memantine to treat his memory lose,confusion and the problems with his thinking and reasoning.just to help slow the progression and manage the symptoms,as no cure exists I read through with interest. I once believed Alzheimer disease has no cure. Well it is true with English medicine, but not with herbal medicine. My Dad experience opened my eyes to the reality of a cure through herbs. My Father was a vibrant man before his encounter with Alzheimer. He was a scientist, hence his mental capability was never in doubt. In 2013, he was diagnosed with Alzheimer. The symptoms manifested through repeating conversation and gradually forgetting things. It became progressive from finding the right words during conversation, to significant confusion and forgetting details about himself. It was not a good experience, seeing your father whose brilliance had no match, totally became a shadow of himself. His doctors said the disease has no cure, just medications for treatment which had a lot of side effects were administered to him. Early 2016, while on the internet, I bumped into a story of Alzheimer, and I read about a cure through herbs with interest. I researched more to be sure it was not a hoax.  In my quest, Doctor James herbal mix medicine was mentioned in the testimony. I contacted him on his email that was provided  (drjamesherbalmix@gmail.com)   and I got his herbal mix medicine for my father.He told me that his herbal mix medicine will help my Dad to reduce the abnormal protein fold inside his neurons,and regulate the nutrients and molecules in his body system,and as well stop the progressive disorder that build up in damaging his brain cells,and help his weak cells  that causes  brain shrinking to function well,its a good herbal drinks for cell reparing.This doctor James is super great man and his herbal mix medicine is wonderful and works effectively as he said,with no side effects. It's been 4 years and my Dad is perfectly okay and back to his laboratory work even at old age. For your loved ones with Alzheimer or Dementia, take them off English medicine and use Dr. James herbal mix medicine for treatment. if you have any kinds of health challenges  or diseases such as..Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer ,Epilepsy Dupuytren's disease ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Sclerosis,Fibromyalgia,Fluoroquinolone Toxicity
    Syndrome Fibrodysplasia Ossificans ProgresS sclerosis,Seizures,Alzheimer's disease,Adrenocortical carcinoma.Asthma,Allergic diseases ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis,Lupus,Cushing’s disease,Heart failure,Multiple Sclerosis,Hypertension,Lyme Disease,Blood Cancer,Brain Cancer,Breast Cancer,Lung Cancer,Kidney Cancer, HIV/AIDS, Herpes Virus,Hepatitis B, Liver Inflammatory,Diabetes,Fibroid. just reach him on his Email  [drjamesherbalmix@gmail.com].   and get your permanent cure.he's a good man and he will help you.

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  3. vera2sweet1@gmail.comMy husband has been diagnosed with Alzheimer's in 2016 there's a herbal foundation in Cape Town they cured my husband  Alzheimer's disease . Pm me i will give their details. People can search about them on Google or youtube (Multivitamin Care ). My husband faced many difficulties and was in several depression, Trouble understanding visual image, aggression ,so many,. This thing happened to him at a very crucial stage of our life. PM if someone needs info or contact them directly Multivitamincare.org  they cured 100% of Alzheimer with their herbal formula .

    ReplyDelete