Wednesday, 28 November 2018

Microbiota age

Different developmental stages of the microbiota can be distinguished. The different developmental stages define the age of microbiota of a human being. Every increase or decrease in the microbiota age compared with the actual chronological age of a child can indicate various outcomes.

After the first microbes colonize the human body, the microbiota start to develop, over the next few years, depending on environmental factors, like food intake. First change will happen during weaning, which starts a non random process of maturation, induced by the change of the nutrient consumption. During the first phase of milk consumption we have Bifidobacteria as a dominant member of microbiome. Upon weaning, members of Firmicutes and Bacteroidetes become dominant. Microbiota reaches adult  stage in 3-6 years, being fully maturated after puberty. Main markers of bacterial adulthood are already present at toddlers. The microbiota of formula fed babies is more mature compared to a breastfed child. The maturation of microbiota also happen faster at c-section born babies.

Maturation of the microbiota is directed by nutrition. Malnutrition in early stages of life can result in irreversible stunted growth and impaired cognitive ability. The microbiota of malnourished children does not mature fully. But a food intervention rescuing children from malnutrition will immediately mature the microbiota. The potential relationship between infant malnutrition and gut microbiota might contribute to food and microbial based therapies for malnourished people. Microbiota -modulation strategies could help restore infant growth and developmental problems. Increase or decrease of microbiota age in comparison with chronological age of the child can be used to find different health outcomes. Immature microbiota is associated with malnutrition, while faster maturation is associated with formula feeding and c-section birth. Because of all these reasons, microbiota-modulation can be the next-step strategy supporting personalized nutrition and microbiota based strategies.

Tuesday, 27 November 2018

Nootropics and other brainy stuff

Sooon, as soon as i got some free time, i will write about nootropics and brain boosters and enhancers. 

See you!

Saturday, 24 November 2018

Awe


I am everybody and every time,
I always call myself by your name.

- Pablo Neruda -

Monday, 19 November 2018

Atomz.io ICO full review


The idea behind ATOMZ project, as it is underlined in the Whitepaper, is: How can one invest easily in cryptocurrencies? What if there is a software or device to signal us the best coin to buy or sell at the present moment? There are 1600+ coins to choose, but only the less known ones tend to accumulate wealth quickly, even if they are hard to track. Today is much easier to buy bitcoin, but some altcoins are still hard to buy. We all know that is good to buy low and sell high, but with the new crypto you never know if a project will fail completely after you buy low or will rise and rise long after you sell at what you were thinking is an all time high. Storage is another problem to solve, and these days if an exchange is hacked, chances to get your crypto back are quite low (see Mt. Gox case, one of the first hacked exchanges who did not pay back yet). Automated trading is another issue at hand, and it is hard to do it, as the good trading bots are quite expensive, not very transparent, not on the cloud (private servers instead) and not very customizable.
The Atomz project aims to make investing easy while generating profit. The proprietary software will analyze trends, rate the cryptocurrencies and determine the best to buy or to sell at any given moment. Help will be available for the beginners. You need to understand that the more blockchain technologies will be available and reach customers safely, the more acceptance they will gain and more value will be created.
The token symbol is ATZ, and the time of the token generation event is not yet known. There will be three phases, first for private investors, 2 millions ATZ at the price of 0.40 USD, second phase for pre-ICO, 3 millions ATZ at the price of 0.60 USD and the last phase, the ICO, with 10 millions ATZ, at the price of 0.8–1 USD. The accepted cryptocurrencies for payment are BTC, ETH, LTC, ETC, BCH and DASH.
The allocation for the tokens will be done like this:
  • 20% team (5 millions ATZ)
  • 40% ICO (10 millions ATZ)
  • 14% pre-ICO (3.4 millions ATZ)
  • 14% investors (3.5 millions ATZ)
  • 12% marketing and other services (3 millions ATZ)
All unsold tokens will be locked for one year and sold later.
Funds distribution will be done like this:
  • 50% research and development
  • 25% operations and admin
  • 15% marketing
  • 5% legal expenses
  • 5% charities.
Let’s take a look at their Roadmap. They started in November 2017 making the journey from idea to first software development, after the team was made. The first functional base software for advice tier and the token sale preparation began in April 2018. In August 2018 they started to recruit private investors and partners to help with the ICO and product development. In November 2018 the pre-ICO sale was organized, to bring additional funds for the project and gain a functional user base. Next steps to follow are:
  • 12.2018 -launch of the ICO public sale and the growth of the Atomz platform;
  • 2.2019 -end of the Atomz ICO, software improvements and team new members if needed, marketing and exchange listing;
  • 6.2019 -closed beta launch, feedback and software improvements;
  • 7.2019 -growth of the platform and new partnerships;
  • 9.2019 -open-beta platform testing and optimizing (community voting, decentralized login/token login, limited user base).
The final product will have 3 tiers (cryptocurrency advice, cryptocurrency mutual funds like, cryptocurrency trading bot). Regarding the cryptocurrency advice, they want to be able to determine the best crypto to buy and sell at any given moment. The cryptocurrency packs, similar with mutual funds, with price being determined automatically. There will be different types of packs: top packs, techno packs, market cap packs. The trading bot is utilizing Atomz index, choosing custom strategies, blacklisting cryptocurrencies if needed, making investing easy and safe.
They claim to use different trends like RSI (relative strength index -to detect if the market is oversold or overbought), MACD (moving average convergence divergence -to detect trends), Bollinger bands to add reliability to RSI and MACD, market cap proportions. There are risks associated with this, the market crash being the biggest risk, adjusted by news investigation, done manually and by AI. Another risk is related to the data gathering -right now it takes 15 minutes to analyze top 100 cryptocurrencies, in the future can go up to 2 hours.
The access to the Tiers can be achieved by paying ETH equivalent of the fee in ATZ. Tier 1 is 0.16 ETH (80 ATZ), Tier 2 is 0.32 (160 ATZ) and the Tier 3 is 0.64 ETH (320 ATZ). Mutual packs and the trading bot can be bought using only ATZ tokens.
To find more about them, you can check the links to Atomz social media:
(Disclaimer: This article was created in exchange for a potential token reward through BountyOx. BountyOx username: Heruvim78)

Thursday, 25 October 2018

Early life microbiome development

Did you ever ask yourself how the microbes enter in your body? Your mom donated many of her beneficial microbes during birth, and she fostered the growth of you and your microbes with her milk, providing nutrients for both you and your microbiota. If you are born by cesarean section your microbiota will develop differently, and this can be linked to later life diseases like allergies and obesity. As an infant, your microbiota was very different, and growing up, it grew up with you. First time receiving solid food was a life changing event for both you and your microbiome.

Each individual has various habitats of microbial communities. The human body is continuously sampling the pool of available environmental microbes. A selection take place for specific microbes that will find their optimal niche in our different body organs. The microbial colonization of humans was thought to begin at birth, but there is evidence of bacterial presence in the placenta, umbilical cord and amniotic fluid of healthy full term pregnancies. This means that microbial exposure started before delivery, allowing the fetus to adapt to microbiota and stimulating the perinatal immune system. Upon and right after the birth a massive amount of microbes enters in contact with the newborn. The colonization of the body by the microbes is influenced by the mode of delivery, type of feeding and/or antibiotic usage. Mothers diet, age and metabolic status, combined with the family genetics and lifestyle are also affecting the infant microbiota development. The colonization it happens vertical (during birth, with microbes from mother lower intestinal tract and vagina) and horizontal (after birth, close contact with siblings, pets, dietary habits). Once the microbes enter in the human body, the conditions of the different body parts are determining which microbes will remain for colonization. The microbiota composition of the stomach, duodenum, ileum and colon are quite different. Acidity, transfer time and nutrients absorption are few of the important factors to select which microbes will adapt to each condition. For example, in the ileum we have a fast transit time (2-6 hours), a thin layer of mucus and the host is continuously absorbing proteins and sugars, so this conditions are sub-optimal for most of the microorganisms.  In the colon is a complete other situation, with a transit time of 24-48 hours, thick mucus layer and many non digested fibers are available to microbes to ferment. This is the reason why the colon is the most densely microbial populated part of human body (10-12th bacteria per gram of feces, about 1 kg of mass in total).

Right after birth, the gastro-intestinal tract is getting colonized first with facultative anaerobic bacteria, which will reduce the oxygen level in the intestine, making it easy for the anaerobic bacteria to survive. This step it will take 1-2 days to complete. The early life microbiota is dynamic, unstable and a significant variation exists between babies. But this is a non-random process, the body selecting the microbes that have adapted to the conditions of the different organs. The exposure to microbes is mainly determined by the more od delivery, type of feeding and antibiotic usage.

Next post will be about the importance of human milk.

Wednesday, 24 October 2018

Microbiome research and causality

Clinicians and biologists try to find correlations between the gut microbioma and health outcomes. Very often no causal link is found. If one is ill for long time, chances are that medications were used regularly, and if one is obese, chances are that he/she ate unhealthy for long time. These factors will influence the onset of the disease and the gut microbioma composition. Even more, other factors like country of origin and the genetic background will also play a role in the gut microbiome composition and in the chance of developing certain diseases. The main challenge is to find out the right changes in the gut microbiome that actually play a role in the disease. Is then the fact that, in a dataset of thousand of bacteria, some of them show a correlation with the disease real or based on sheer coincidence?

A good example of causal relationship between the gut microbiota composition and the development of a disease is fecal macrobiota transplantation. This strategy was applied for patients with Clostridium difficile infections and the results were good, as this microorganism is able to thrive in people with disturbances in their gut microbioma, but a fecal transplant of a healthy gut microbiome composition will restore the balance and get rid of C.difficile bacteria. Another interesting development in the study of the healthy microbiome shows that the bacterium Akkermansia Muciniphila is abundant in healthy people but often absent or low in human or mice  with obesity. If you feed them with A. muciniphila, a relation between the bacteria and the metabolic health of the host is noted, and a positive effect on health balance and metabolic rate. An ongoing clinical trial with pre-diabetic patients is done right now in order to confirm those positive effects.

Other option to study causal relations between gut microbiome and health can happen in laboratory, using germ free mice, and exposing them to specific bacteria to test the effect on metabolism, digestion or immune system. But we cannot have a decisive answer using these methods, and a clinical trial using an appropriate group of patients is always needed, hopefully resulting in personalized treatments against diseases, taking into account the differences in our microbiome.

Microbiota is defined as everything staying in our gut, small enough to not be seen with naked eye (bacteria, archaea, fungi and viruses) and their habitat. Microbes form our gut play a role in all kind of systems to good liver access, good brain access, good skin access. The microbiota is personalized, everybody has a different microbiome. Monozygotic twins are more similar than average unrelated individuals in terms of microbiome, and this can be because genetics or same time colonization. The microbiome develops through life, so some of our actions will impact later in life (as repeated use of antibiotics for example). We have an enormous number of associations between our microbes and our cells activities, but no casualty (the famous example with recurrent C. difficile patient in intensive care and almost dying being rescued by fecal microbiota transportation in a systematic way, much better than antibiotics).

We got MetaHit project, with over 3 millions genes discovered in the guts of a couple of people, aiming to understand what is it there in our microbiota, but also what is their function, how they are expressed, how they are collaborating and constituting this ecosystem that makes us healthy. There is a symbiosis relationship (Venom is a great movie about symbiosis, by the way) and we feed the microbes that we want to have in our gut. As important hallmark of our discoveries in the last couple of decades, Akkermansia Muciniphila (the gatekeeper of mucus) reinforces our gut barrier and prevents substances like LPS to come into our bloodstream.

In the next posts i will talk about the early life microbiota development.
Have a nice day!
G.







Saturday, 20 October 2018

New Neuroscience Reveals 7 Secrets That Will Make You Persuasive



***
by Eric Barker


You can painstakingly show somebody tons of bulletproof evidence and present flawless logical arguments but often they still won't change their mind. What gives?

The problem is that the human brain is not a purely rational computer. And when we ignore that, even the best of efforts to convince others can fall flat.

From The Influential Mind:

As it turns out, while we adore data, the currency by which our brains assess said data and make decisions is very different from the currency many of us believe our brains should use. The problem with an approach that prioritizes information and logic is that it ignores the core of what makes you and me human: our motives, our fears, our hopes and desires. As we will see, this presents a serious problem; it means that data has only a limited capacity to alter the strong opinions of others.

So the human brain doesn't work by strictly logical rules -- but it does work by rules. And if we know what they are, we have a much better shot of framing our arguments in ways that other people will find convincing.

So what are these rules? Don't look at me -- I'm the guy who presents heaps of data all the time thinking that makes a difference. (Sigh.) That said, I know where we might be able to get some answers...

Tali Sharot is a professor of cognitive neuroscience at University College London and her new book is The Influential Mind: What the Brain Reveals About Our Power to Change Others.

She's identified 7 factors that influence our ability to influence. (I hope you don't mind if I try to change your mind about how to get others to change their mind.)

Let's get to it...


1) Prior Beliefs

Don't ignore a person's current stance when trying to persuade. Military strategy says direct assaults against fortified defenses are stupid. The human brain is no different. Start off by telling people they're wrong and you're already in trouble.

When our brains hear new info that agrees with our beliefs, we eagerly accept it. When we hear things that contradict our beliefs, our minds suddenly morph into defense lawyers looking for any conceivable flaw.

So a few rounds of back-and-forth jousting doesn't weaken people's opposition. Often it has a "boomerang effect" that ironically causes them to double down.

From The Influential Mind:

When you provide someone with new data, they quickly accept evidence that confirms their preconceived notions (what are known as prior beliefs) and assess counterevidence with a critical eye. Because we are often exposed to contradicting information and opinions, this tendency will generate polarization, which will expand with time as people receive more and more information. In fact, presenting people with information that contradicts their opinion can cause them to come up with altogether new counterarguments that further strengthen their original view; this is known as the "boomerang effect."

You're a pretty smart person, right?

Well, that means you're more likely to boomerang, not less. (If you responded by saying, "No, I'm a moron" then you're off the hook.)

From The Influential Mind:

...the greater your cognitive capacity, the greater your ability to rationalize and interpret information at will, and to creatively twist data to fit your opinions. Ironically, then, people may use their intelligence not to draw more accurate conclusions but to find fault in data they are unhappy with.

So how do we overcome this natural neuroscientific resistance? Don't begin by trying to prove others wrong. Start by finding common ground.

When people who believe childhood vaccination is dangerous were presented with evidence that it's not, the discussion went nowhere. When the focus was shifted to "improving the health of children" the conversation made progress.

From The Influential Mind:

Influence behavior by building on common ground instead of trying to prove others wrong. Our instinct is to try to alter people’s beliefs and actions by introducing data to prove that we are right and they are wrong. It often fails, because in the face of facts that clash with their prior beliefs, people tend to come up with counterarguments or turn away. Instead, find arguments that rely on common ground. For example, telling parents who refuse to vaccinate their children that science has shown that vaccines do not cause autism did not alter the parents’ behavior. Instead, saying that vaccines would protect their children from deadly diseases was more effective—the argument did not contradict their prior beliefs and was compatible with the common goal of keeping children healthy.

(To learn more about the science of a successful life, check out my bestselling book here.)

So taking the right angle with your logic can be critical. But there's also a way to succeed that is usually considered the exact opposite of logic...


2) Emotion

We all know that our mood affects our judgment. Neuroscience research shows that we actually understand each other better when our brains are "in sync" emotionally.

I tell a joke. You laugh. I laugh. And then the conversation seems to go more smoothly. The positive emotion synced our grey matter. This is one of the reasons that stories can be so powerful in convincing people even when rational arguments fail.

You can have the best evidence in the world, but if you're emotionally out of sync with the other person they might not even really be hearing what you're saying.

From The Influential Mind:

Lauri Nummenmaa, a Finnish neuroscientist who studies brain synchronization, writes that this may be one of the roles of emotion in neural synchronization—to promote social interaction and understanding, and to therefore enhance our ability to predict each other’s actions… Emotion equates the physiological state of the listener with that of the speaker, which makes it more likely that the listener will process incoming information in a similar manner to how the speaker sees it. This is why eliciting emotion can help in communicating your ideas and having others share your point of view, whether you are conversing with just one individual or talking to thousands.

So don't neglect to share feelings. Make a joke. Tell a story. Don't try and connect with reason until you've connected with emotion.

From The Influential Mind:

One of the most powerful ways to communicate ideas effectively is to share feelings. Emotions are especially contagious; by expressing feelings ourselves we are shaping other people’s emotional states, and by doing so we make it more likely that the people in front of us will take on our point of view.

(To learn the science of how to take naps that will make you smarter and happier, click here.)

This is all great for ideas. But how do we get people to change their behavior?


3) Incentives

If you want people to do something, emphasizing rewards is powerful.

In one hospital the staff was only washing their hands thoroughly 10% of the time. (I'll pause a second to let your horror die down a bit.)

But when researchers set up an electronic scoreboard that congratulated employees after a good scrubbing, compliance went up to 90%.

From The Influential Mind:

The researchers placed an electronic board in each room giving the staff immediate feedback on how they were doing. Every time a doctor, nurse, or other worker washed their hands, the numbers on the board went up. These figures indicated how well the current shift was going: what percentage of workers were currently washing their hands and what the weekly rate was. What happened? Compliance soared to almost 90 percent!

Anticipation of rewards usually beats fear when it comes to getting people's brains to act. This is one of the reasons why video games can be so addictive.

From The Influential Mind:

If you want someone to act quickly, promising a reward that elicits an anticipation of pleasure may be better than threatening them with a punishment that elicits an anticipation of pain. Whether you are trying to motivate your team to work harder or your child to tidy their room, remember the brain’s “Go” reaction. Creating positive anticipation in others—perhaps a weekly acknowledgment on the company website of the most productive employee or the possibility of finding a beloved toy under a pile of clothing—may be more effective at motivating action than the threat of a pay cut or a time-out.

But it's also vital to keep the other side of this equation in mind. When you want people to stop doing something, warnings about negatives prove more powerful than incentives.

From The Influential Mind:

...when your goal is to cause someone else not to do something—a child to avoid eating a cookie or an employee to avoid communicating confidential information to unauthorized individuals—warning of bad consequences may be more effective than promising rewards.

(To learn how to best use caffeine — from a neuroscientist — click here.)

Focusing on rewards is a much better way to tell people what to do. But, then again, people hate to be told what to do. So the answer to getting people to do what they're told is not to tell them what to do...


4) Agency

People like to feel in control. This isn't just a personal preference; we're biologically wired to seek control. It makes us happier and healthier across a number of dimensions.

From The Influential Mind:

...all else being equal, cancer patients who have a greater perception of control survive longer. Lower risk of cardiovascular disease has also been associated with a greater perception of control. This is not surprising; the sense of control reduces fear, anxiety, and stress—all things that have a detrimental effect on our bodies.

Former FBI lead international hostage negotiator Chris Voss says it's critical in any negotiation to give the other side a feeling of control. And the research agrees.

So when you want to persuade, don’t give orders; give options. Don’t tell; ask and guide.

From The Influential Mind:

...giving people an opportunity to advise how their taxes should be allocated increased the likelihood that they would pay them in full. To produce impact, we often need to overcome our instinct to control and instead offer a choice… What is interesting is that the sense of control need only be that—a perception. It is better to guide people toward ultimate solutions while at the same time maintaining their sense of agency, rather than to give orders.

(To learn how to use FBI hostage negotiation techniques to lower your bills, click here.)

All of this stuff is great but it'll be useless if they're not really paying attention in the first place. So how do you make people want to listen to you?


5) Curiosity

In general, our brains seek positive information and avoid negative information. This is true to an absolutely terrifying degree...

When doctors tell people they may have Huntington's Disease, very few actually follow through on getting tested. Other studies have shown similar results when it comes to HIV testing and breast cancer screening. When the news could be bad, people often don't want to hear it.

From The Influential Mind:

When potential carriers are asked if they intend to take the test, between 45 and 70 percent say yes. Yet most of them do not follow up on their explicitly stated intention. In fact, one study reported that when approached by the registries of testing centers, only 10 to 20 percent of people at risk for Huntington’s choose to register for the test...

So if we frame the info we have as bad, people will often tune out. But if the same information is presented as positive, others often get curious. But how do you make them really curious?

When we hear something that sounds good, but the information is incomplete, your brain wants to "fill the gap." Best example?

"Here are 7 clickbait headlines that will make you more curious."

From The Influential Mind:

...consider online clickbait such as “The ten celebrities you never knew were enthusiastic gardeners” or “The three politicians you never knew got a nose job.” Those create gaps of knowledge in people’s mind that were not there to begin with. I never considered which celebrity adores plants or which politician used to have a crooked nose, but now that this gap of knowledge had been pointed out to me, I have an urge to fill it. Once we are told what we do not know, we want to know.

So to draw people in emphasize the possibility of improvement and highlight the informational gap so they start asking questions.

From The Influential Mind:

Reframe the message to highlight the possibility for progress, rather than doom. Our intuition is that if we have something important to convey, others will want to know it. This instinct is wrong. In particular, if the information is tied to a bleak message, many will actively avoid it—as was the case with preflight safety briefings. Reframe your message so that the information you provide will induce positive feelings (as the airlines did), highlight the informational gap you are filling, and show how the knowledge can be used for the better.

(To learn 6 rituals from ancient wisdom that will make you happy, click here.)

So you're emphasizing the positive benefits that can come from listening to you. That's great. Unless it's not. Because there's an exception to this rule...


6) State Of Mind

When we feel threatened, we're much more sensitive to negative information.

From The Influential Mind:

We found that under threat, people were much more inclined to take in negative information—such as learning that the likelihood of being robbed is higher than they’d thought—than when they were relaxed. The more stressed they were, the greater their tendency to alter their views in response to unexpected bad news. (Stress did not affect the ability of good news to change their beliefs.) Under threat, we automatically absorb cues about danger.

When we feel bad, our instinct is to play it safe -- even if this isn't the smart move. Research shows that when underdog football teams start losing, they play more conservatively. And this is a terrible strategy when the competition is better than you are.

From The Influential Mind:

Examining over one thousand football games from 2002 to 2006, Brian Burke, the creator of Advanced NFL Stats, a website about football and game theory, found that underdog teams, like Tedford’s, were less likely to vary their play. When they begin failing, they start minimizing risk. …a conservative strategy means underdog teams are less likely to fail grandiosely, but they are also less likely to win.

On the other hand, when we feel good we're more inclined to take risks. Researchers theorize that positive emotions make people buy more lottery tickets. When you feel good, you feel lucky.

From The Influential Mind:

Examining lottery sales in New York City, Ross Otto and his colleagues from New York University stumbled on a peculiar pattern. When unexpected good events happened, more people bought lottery tickets. A local sports team unexpectedly won a game? Purchases escalated. An atypical sunny day in the midst of winter? Sales went up. This study is correlational—it shows a relationship between variables, but we do not know whether one factor is driving another. However, one theory is that an unexpected positive event, such as a bright, sunny day, makes people feel good. When you are joyful and relaxed, your mind is more likely to focus on how things may go your way. You may then overestimate your luck and be more inclined to take a risk.

So align your presentation with the other person's mood. When they're feeling down, they'll be more receptive to suggestions that seem safe. When they're up, they'll be responsive to riskier ideas that have a big payoff.

From The Influential Mind:

A person’s emotional mind-set will affect how they react to what you have to say. There needs to be a match between the opinions we are offering and the state of the individual in front of us. The same person will ignore your guidance one day but welcome it with open arms another, simply because their favorite football team lost last night or because the sun is shining on a winter day.

(To see the schedule that very successful people follow every day, click here.)

Finally, it's important to keep in mind that when you're trying to persuade someone the two of you aren't the only ones who can affect the result...


7) Other People

We're social creatures. We love to think we act independently and aren't affected by the opinions of others, but we are. Always and forever.

This is so powerful that we follow the lead of others even when it can be life-threatening.

From The Influential Mind:

...every year, 10 percent of kidney donations in the United States go unused. It turns out that when a donation is declined by one patient, whether because of the patient’s specific medical condition or their religious beliefs, the next patient on the list is informed that the organ was previously declined but is not told the reason. That patient then assumes that the organ is faulty and passes up a potentially lifesaving operation—as will the next patient, and the next.

The flip side is just as true. When others are positive about something, we're more likely to see it positively as well.

From The Influential Mind:

Sean Taylor, who received his PhD from NYU and now works for Facebook, has studied how existing ratings and comments influence subsequent ratings. He found that if you manipulate the ratings so that the first review is glowing, the likelihood of other positive reviews increases by 32 percent and the final rating is enhanced by 25 percent!

When we frame our position as a positive and popular one it gives it more weight because, hey, all the cool kids are doing it.

(To learn the four Stoic secrets to being more productive, click here.)

Okay, we've covered a lot. Time to round it all up...


Sum Up

Here's how to use neuroscience to be more persuasive:

Prior Beliefs: Don't start with how they're wrong, start with common ground. (You may disagree with me on this but we both want to get better at persuasion, don't we?)

Emotion: Make them feel and get your brains in sync. (Look! Smiling puppies!)

Incentives: Focus on rewards, not warnings. (Incentives will get you what you want, I promise.)

Agency: Give options, not orders. (Would you like to offer them two possibilities or three? Totally up to you.)

Curiosity: "Fill the gap" and focus on the positive. (The headline of this blog post was not chosen at random, my friend.)

State of Mind: If they're feeling down, present the conservative option. If they're feeling good, focus on the riskier upside. (Before I explain this further, how are you feeling today?)

Other People: Showing the popularity of your position helps. (Every smart person I know follows this rule.)

That's all the data you need to stop being reliant on data. We didn't have statistics and research thousands of years ago but people still convinced one another.

We get the answers we need when we think like a computer.

But we get the help we need when we don't forget we're human.